Ketone body can be a fuel substrate for failing heart
نویسندگان
چکیده
منابع مشابه
The failing heart--an engine out of fuel.
Copyright © 2007 Massachusetts Medical Society. Heart failure is an enormous medical and societal burden.1,2 It is a common disease: more than 2% of the U.S. population, or almost 5 million people, are affected, and 30 to 40% of patients die from heart failure within 1 year after receiving the diagnosis.3 Heart failure can be disabling, and it can severely reduce a patient’s quality of life. It...
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The alterations in myocardial energy substrate metabolism that occur in heart failure, and the causes and consequences of these abnormalities, are poorly understood. There is evidence to suggest that impaired substrate metabolism contributes to contractile dysfunction and to the progressive left ventricular remodeling that are characteristic of the heart failure state. The general concept that ...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2019
ISSN: 0008-6363,1755-3245
DOI: 10.1093/cvr/cvz104